Science is the key to overcome infertility – We call it ReproScience

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ReproScience is initiating over 20 new cross-border projects with more than 20 new research positions in order to overcome infertility.

ReproScience’s objective is to create a High Competence Centre in reproductive medicine. This requires an enhanced cooperation between the Danish and Swedish research groups. Therefore, we are initiating over 20 new cross-border projects during the project period with more than 20 new research positions. This will connect the Oresund region’s main competencies and strengthen the scientific quality. In the long term this will keep the region world leading in managing and preventing infertility problems.

Historically, the Oresund region – also known as Medicon Valley – has a high international position within reproductive medicine in relation to patient management and research. However, there is a need to strengthen the collaboration between the partners at hospitals, universities and industry, in order to maintain and develop the field.

ReproUnion represents more than 50 PhD students and approximately 30 senior researchers. The clinics who are partners of ReproUnion have access to large patient materials, including 4000 IVF/ICSI cycles per year, 1500 seeking andrological management and 6000 semen analyses.

The key clinical competences include:

  • High standard IVF and ICSI treatment including use of recent methods for embryo selection;
  • Extended evaluation of the male partner in order to find the best treatment options for the couple and prevent long term squeal of infertility;
  • Sperm DNA analysis;
  • Andrological surgery and treatment of ejaculatory dysfunction;
  • Gonadal cryopreservation;
  • Gamete donation;
  • Assessment and counselling regarding environmental reproductive risks at the individual and the group level

With these competences, we are able to overcome infertility together.

Watch the videos with the senior researchers and learn more about their visions for the ReproUnion project.

Overview of ReproScience projects

The following science projects are currently under development within the ReproUnion framework. Click on a project title to read more about each project.

Click here to browse the graphical list of project.

Project

ID

PhD/PostDoc

Principal Investigater

Organisation

Fetal Programming of Semen quality BBH1 Katia Keglberg Haervig and Birgit Høyer  

Jens Peter Bonde and Elvira Vaclavik Bräuner

Bispebjerg Hospital
Department of Occupational and
Environmental Medicine
Male and female infertility as a precursor of chronic disease and mortality BBH2 Clara Helene Glazer  

Jens Peter Bonde and Elvira Vaclavik Bräuner

Bispebjerg Hospital
Department of Occupational and
Environmental Medicine
Reducing the Impact of Ovarian sTimulation – RIOT A HER1 Agnieszka Warzecha Sven O. Skouby Herlev Hospital
Department of Gynaecology and Obstetrics
Reducing the Impact of Ovarian sTimulation – RIOT B HER2 Agnieszka Warzecha Sven O. Skouby Herlev Hospital
Department of Gynaecology and Obstetrics
Age and follicle DNA methylation profile HER3 Kristina Wendelboe Olsen Marie Louise Grøndahl Herlev Hospital
Department of Gynaecology and Obstetrics
Surgical sperm retrieval in non-obstructive azoospermic men – a randomized trial HER4 Christian Fuglesang

S. Jensen

Jens Sønksen Herlev Hospital
Department of Urology
Identification of ovulation related genes and pathways in human follicles at different stages of oocyte maturation HOL1 Liv la Cour Poulsen Anne Lis Mikkelsen Englund Holbæk Sygehus
The Fertility Clinic
MicroRNA as a biomarker for development of metabolic syndrome in women with Polycystic Ovary-Syndrome HOL2 Pernille Bækgaard Udesen Anne Lis Mikkelsen Englund Holbæk Sygehus
The Fertility Clinic
Freeze all and transfer later HVI1 Sacha Stormlund Anja Pinborg Hvidovre Hospital
Department of Gynaecology and Obstetrics
The association between fetal exposure to endocrine disrupters cerebral palsy LUND1 Anna Jöud and Andrea Sehlstedt Lars Rylander Lund University
Department of Occupational and
Environmental Medicine
The association between air pollution and preeclampsia LUND2 Ebba Malmqvist  Ebba Malmqvist Lund University
Department of Occupational and
Environmental Medicine
Testosterone proteomics study (TP study) LUND3 Barbara Sahlin PhD Johan Malm Lund University
Department of Clinical Chemistry Malmö
Sperm DNA strand breaks in relation to infertility treatment and the health of the   M1  Amelie Stenquist  Aleksander Giwercman Lund University
Department of Translational
Medicine Malmö
Cancer treatment and genetic instability in relation to the health of the offspring M2 Yahia Al-Jaberi Aleksander Giwercman Lund University
Department of Translational
Medicine Malmö
Stratified treatment in ovarian hyper stimulation M3 Nishtman Dizeyi Yvonne Lundberg Giwercman Lund University
Molecular Genetic Reproductive Medicine, Malmö
Auto-transplantation of fragmented ovarian cortical tissue in infertile patients with low ovarian reserve – a study to promote follicular activation and fertility RH-FC1 Stine Lunding Anders Nyboe Andersen Rigshospitalet
The Fertility Clinic
Infertility and membrane fusion – The role of Syncytin in membrane fusion of human egg and sperm cells RH-FC2 Marie Berg Nygaard Søren Ziebe Rigshospitalet
The Fertility Clinic
Ovarian reserve parameters in long-term combined oral contraceptive use, and knowledge and concerns about fertility after long-term use – A prospective study of Danish women RH-FC3 Selma Kløve Landersø Anders Nyboe Andersen Rigshospitalet
The Fertility Clinic
New method to quantify INSL3 by LC-MS/MS: A new diagnostic marker for Leydig cell function RH-GR1 Jakob Albrethsen Anders Juul Rigshospitalet
Department of Growth and Reproduction
Semen quality: A marker of health RH-GR2 Lærke Priskorn Anders Juul Rigshospitalet
Department of Growth and Reproduction
Identification of genetic and epigenetic variation influencing gonadal function RH-GR3 Nina Mørup Anders Juul Rigshospitalet
Department of Growth and Reproduction
The concentration of carbon fluoride and paracetamol in human embryos RH-LRB1 Linn Salto Mamsen Claus Yding Andersen Rigshospitalet
Laboratory of Reproductive Biology
Development of new methods to preserve fertility in pre-pubertal Danish and Swedish boys, who have a risk of a destroyed testis function RH-LRB2 Lihua Dong Claus Yding Andersen Rigshospitalet
Laboratory of Reproductive Biology
Growth activation of resting ovarian follicles – a novel approach for fertility treatment and preservation RH-LRB3 Susanne Pors Claus Yding Andersen Rigshospitalet
Laboratory of Reproductive Biology